
Retinol
The gold-standard dermatological molecule that resurfaces skin and targets deep wrinkles. The combination of pure and gradual retinol allows a significant corrective dose to be delivered continuously.
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La Roche Posay Retinol B3 Serum is designed for people looking to improve skin texture and reduce the appearance of fine lines. The serum combines pure retinol with niacinamide (Vitamin B3) in a lightweight formula that's dermatologist-tested and suitable for sensitive skin. Apply a few drops to clean, dry skin in the evening, starting with 2-3 times per week and gradually increasing frequency as tolerated.
Revitalize Your Skin with Retinol B3 Serum
Experience the power of La Roche Posay's advanced Retinol B3 Serum. This premium face serum combines pure retinol with niacinamide (Vitamin B3) to help improve the appearance of your skin, leaving it looking smoother, more radiant, and youthful.
Perfect For:
Those seeking a revitalizing serum to help improve skin texture, enhance radiance, and maintain a youthful-looking complexion.
How to Use:
Apply a few drops to clean, dry skin in the evening. Gently massage into face and neck, avoiding the eye area. Follow with your moisturizer. Use sunscreen during the day. Start with 2-3 times per week and gradually increase frequency as tolerated.
Why You'll Love It:
La Roche Posay's dermatologist-tested formula delivers professional-grade skincare with gentle effectiveness. The combination of retinol and B3 works to help your skin look and feel its absolute best.
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Estimated delivery: 1–3 business days
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La Roche-Posay is the world's most prescribed dermocosmetic brand, trusted by dermatologists across 34 countries. With a legacy of combining pharmaceutical expertise and skincare innovation, the brand delivers life-changing formulations designed to address real skin concerns. Every product is developed with dermatological precision to ensure efficacy and safety for all skin types.
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The gold-standard dermatological molecule that resurfaces skin and targets deep wrinkles. The combination of pure and gradual retinol allows a significant corrective dose to be delivered continuously.

An active ingredient that improves the skin barrier with intensive soothing properties and decreases redness.

A moisturizing active ingredient that helps repair and protect the skin barrier.
Use 3 to 4 drops of the product. Apply morning and/or night. Apply on the face, neck and decollete. Apply on a cleansed face and use UV protection after using this serum.
Specs last updated: May 16, 2026
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★★★ Skin feels smoother and looks brighter after a few weeks. Retinol works gently with B3 so no harsh irritation. Worth it.
★★★ Helped fade dark spots and fine lines without drying me out. Texture improved a lot and makeup sits better now.
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